Pulmonary Embolism Rule Out Criteria (PERC) Age ≥ 50 years Patient under 50 years old? Heart Rate ≥ 100 bpm Current heart rate below 100? SpO₂ < 95% Room air oxygen ≥95%? Estrogen Use No recent hormone therapy? Recent Trauma/Surgery No surgery/trauma in 4 weeks? Hemoptysis No blood in sputum? DVT Symptoms No leg swelling/pain? Prior VTE No history of clots? Assess PE Risk PERC Rule Guidelines Applies only to low-risk patients (clinical gestalt estimate of PE probability <15%) Validated in emergency department settings Negative PERC: PE excluded (NPV 97-99%) Positive PERC: Requires further testing (D-dimer/CTPA)